Sets & Collections
Triple Cell Renewal Trio
$385
A SeneGence set: Climate Control, GLP-Complex, SeneCell Concentrate.
What’s inside
- Climate Control
- GLP-Complex
- SeneCell Concentrate
The full review
Triple Cell Renewal Trio review: my honest take
ReviewCompareRoutineInsideSetsTipsFAQs
Pieces3 full products
Key techSenePlex+
Price$385
Set savingNone vs singles
The Triple Cell Renewal Trio is SeneGence’s new top-shelf anti-aging set: Climate Control, GLP-Complex with SenePlex+ and Exosomes and SeneCell SenePlex+ StemCell Concentrate. All three carry SenePlex+, the complex SeneGence says helps reduce signs of aging while moisturizing. SeneCell has the highest SenePlex+ dose in the range.
Three serums is a commitment. Start with the one that matches your biggest worry, then build.
Each piece has its own job. Climate Control is a hydrating gel essence with Aquaxyl and glucosamine. GLP-Complex uses centella plant exosomes and peptides, aimed at volume loss, deep wrinkles and firmness. SeneCell adds orchid stem cells and cross-linked hyaluronic acid for lines, hydration and firmness. It’s a lot of product for one routine, and it sits on top of your cleanser and moisturizer, not instead of them.
At $385 the trio costs exactly the three singles added up ($85 + $155 + $145), so there’s no bundle discount. It makes sense if you already want at least two of the three. If you’re newer to serums, start with Climate Control alone at $85 and add GLP-Complex or SeneCell later.
Best for
Mature skin that already has a basic routine and wants SeneGence’s most advanced anti-aging layer.
Skip it if
You’re new to serums or on a budget. Start with Climate Control or GLP-Complex on its own.
Triple Cell trio vs GLP-Complex vs SeneCell: which one should you get?
| Triple Cell Renewal Trio | GLP-Complex My pick | SeneCell Concentrate | |
|---|---|---|---|
| What you get | Climate Control, GLP-Complex, SeneCell | 1 serum, 1.66 fl oz | 1 concentrate, 1.66 fl oz |
| Aimed at | Hydration, volume, lines, firmness | Volume loss, deep wrinkles, firmness | Cell renewal, lines, hydration |
| Standout | All three SenePlex+ steps | Plant exosomes, peptides | Highest SenePlex+ dose |
| Price | $385 | $155 | $145 |
| Pick it if | You want the full system | Loss of volume is your main concern | You want the strongest SenePlex+ step |
Where it fits in your evening routine
1Melt-Away Cleansing Balmremove makeup2Facial Resurfacerexfoliate3Triple Cell Renewal Trioyou are here4Evening Moisturizeryour skin type
The trio sits in the advanced anti-aging step of SeneGence’s regimen, after cleansing and exfoliating and before moisturizer. My notes don’t give an official order for the three, so go thinnest first: Climate Control, then the two serums. Finish with the Evening Moisturizer for your skin type.
What’s in the set piece by piece
- Climate Control: a hydrating gel essence with SenePlex+, Aquaxyl (a sugar complex SeneGence says supports the skin barrier and moisture) and glucosamine. 2.85 fl oz.
- GLP-Complex with SenePlex+ and Exosomes: centella asiatica plant exosomes, Adipofill’in, ChroNOline peptide and SenePlex+, aimed at volume loss, deep wrinkles and firmness. 1.66 fl oz.
- SeneCell SenePlex+ StemCell Concentrate: orchid stem cells, Marimoist and cross-linked hyaluronic acid, with the highest dose of SenePlex+ in SeneGence’s range. 1.66 fl oz.
Other sets worth a look
- Collagen Firming Night Pak w/ Brush: firming night pak with an applicator brush, $110
- Microbiome SkinCare Regimen Set: 4 steps for sensitive skin, with SPF 15, $290
- Normal-Dry SkinCare Regimen Set: SeneGence's core 4 steps, $265
My tips
Tip 1
Wait a minute between layers so each one sinks in; stacking three serums fast can feel tacky.
Tip 2
Introduce one product per week so you can tell which one your skin likes, and which it doesn't.
Tip 3
Climate Control also works as a quick midday refresh over bare skin on dry, windy days.
❦
Triple Cell Renewal Trio FAQs
What's in the Triple Cell Renewal Trio?
Climate Control, GLP-Complex with SenePlex+ and Exosomes, and SeneCell SenePlex+ StemCell Concentrate. That’s three full-size products, all built around SenePlex+.
Does the Triple Cell Renewal Trio save money?
No. At $385 it’s the same as buying Climate Control ($85), GLP-Complex ($155) and SeneCell ($145) separately. You’re paying for the convenience of one order.
What order do you apply Climate Control, GLP-Complex and SeneCell?
My notes don’t include an official order. A good rule is thinnest texture first, so start with the Climate Control gel essence, then the serums, then moisturizer.
What does SenePlex+ do?
SeneGence describes SenePlex+ as a proprietary complex that helps reduce the visible signs of aging while moisturizing, and says it doubles cell renewal in 18 days.
Is the Triple Cell trio worth it if I'm in my 30s?
It’s aimed at volume loss, deep wrinkles and firmness. If those aren’t your concerns yet, Climate Control or SeneSerum-C alone is a more sensible start.
Add to the routine
